Peripheral neuropathy is a disease or degenerative state of peripheral nerves in which motor, sensory, or autonomic nerve fibers may be affected. Polyneuropathy is a generalized, roughly symmetric hereditary or acquired disorder affecting peripheral nerves. It is the most common form of peripheral neuropathies. Small-fiber neuropathy is a subtype of sensory neuropathies, which exclusively or predominately affects small diameter fibers (Aδ) and unmyelinated (C) fibers.

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